Motor fatigue measurement by distance-induced slow down of walking speed in multiple sclerosis.

A highly significant deceleration was consistently observed in more disabled pMS with an EDSS 2.5–3.5 and 4.0–6.0 ( Figure 2A ), a MrWD between 500 and 4000 m ( Figure 2B ) or Kurtzke FS scores at 2 or 3 in the pyramidal, cerebellar or sensitive systems ( Figure 2C, 2D and 2E , respectively).

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