HD mouse models reveal clear deficits in learning to perform a simple instrumental response.

Kaplan-Meier analysis was not possible in the 74 week group since no z_Q175 homozygous animals acquired the response within the available timeframe (also note the small n in this cohort) but analysis of the 53 week animals confirmed that there were highly significant differences amongst the groups, Logrank (Mantel-Cox) χ 2( 2 ) = 32.8, p < 0.0001 .

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