Barely Significant
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Alternative polyadenylation and nonsense-mediated decay coordinately regulate the human HFE mRNA levels.

PLoS One · 2012 · PMC3329446 · PMID 22530027

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highly significantno p-value reported
Large scale analyses have shown that at least ten single-base variants of the AAUAAA and AUUAAA sequences can also be found with a highly significant occurrence rate potentially representing about 22% of all polyadenylation signals [45] .

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.