Transcriptional hallmarks of Noonan syndrome and Noonan-like syndrome with loose anagen hair.

Hum Mutat · 2012 · PMC3332054 · PMID 22253195

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highly significantno p-value reported

Interestingly, this analysis documented that the PTPN11 signature displayed highly significant enrichment in targets of tyrosine kinases, particularly SRC family kinases (FYN, LYN, LCK, SRC) and SRC family interacting kinases (CSK, SYK, ZAP70).

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