MiR-133b targets antiapoptotic genes and enhances death receptor-induced apoptosis.

PLoS One · 2012 · PMC3332114 · PMID 22532850

Europe PMC DOI

hedged sentences

0.0100

closest p · 0.2× alpha

0.0600

boldest claim

The sentences

highly significantP-value>0.01actually significant

A 1.5-fold change expression cut-off for ratio experiments was applied together with anticorrelation of ratio profiles rendering the microarray analysis highly significant (P-value>0.01), robust and reproducible.

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borderline significancep = 0.06so close (0.05 < p ≤ 0.1)

Univariate Cox regression of continuous miR-133b ratio showed borderline significance of miR-133b as predictive marker for biochemical relapse (HR = 0.16; 95% CI = 0.02–1.06; p = 0.06).

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