Loss of anti-viral immunity by infection with a virus encoding a cross-reactive pathogenic epitope.

Interestingly, an even more and highly significant positive correlation ( p = 0.004, n = 18) was seen if the ratio between the cross-reactive NP205-specific CD8 T cells and the PV NP38-specific CD8 T cells was plotted against the severity of AFN ( Figure 6C ).

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