Successful treatment of fetal intraperitoneal administration of immunoglobulin in a case of fetal hemolytic anemia with 131,072-fold anti-e alloimmunization.

Although there is a chance of puncturing the umbilical cord during IFAC, having obtained a live birth safely in the present case through the direct administration of immunoglobulin to the fetus without the need for intrauterine blood transfusion, even when the indirect Coombs' test antibody titer had increased as high as 131,072-fold, can be regarded as highly significant.

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