Barely Significant
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Clusters of ancestrally related genes that show paralogy in whole or in part are a major feature of the genomes of humans and other species.

PLoS One · 2012 · PMC3338513 · PMID 22563380

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highly significantno p-value reported
In this present study our aim is to obtain new metrics and catalogues of clustered genes that both share structural features detected at the domain level and are highly significant in their proximity to one another, while allowing for sequence divergence to extend to the superfamily level.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.