Barely Significant
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ERF5 and ERF6 play redundant roles as positive regulators of JA/Et-mediated defense against Botrytis cinerea in Arabidopsis.

PLoS One · 2012 · PMC3338558 · PMID 22563431

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The sentences

highly significantp = 2.24 e-11actually significant
Functional enrichment analysis of this set of 46 genes using FatiGO ( http://babelomics.bioinfo.cipf.es ) revealed a highly significant enrichment (Fisher exact test, two-tailed, p = 2.24 e-11 ) for genes annotated with gene ontology (GO) term GO:0006952 (defense response), with 39.1% (18/46) of the upregulated genes associated with this term, compared to 2.61% in the whole Arabidopsis genome.

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