Complex reorganization and predominant non-homologous repair following chromosomal breakage in karyotypically balanced germline rearrangements and transgenic integration.

Nat Genet · 2012 · PMC3340016 · PMID 22388000

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closest p · 0.0× alpha

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boldest claim

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highly significantp = 2.6×10−55actually significant

When we compared these data to the breakpoint homology from 16,783 CNV breakpoints assembled for the 1,000 Genomes Pilot 1 study using identical methods, we find a highly significant difference from either the BWA-SW analysis (χ 2 = 244.6, 1 d.f., p = 2.6×10−55) or the EMBOSS method (χ 2 = 201.6, 1 d.f., p = 1.26×10−45) ( Fig. 3 ).

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