Association of the CpG methylation pattern of the proximal insulin gene promoter with type 1 diabetes.

However, as shown here, CpG residues in a given region may show variable degrees of association between their level of methylation and the disease, ranging from hypo- to hyper-methylation, and from nonsignificant to highly significant levels of statistical association.

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We detected only a small trend of correlation of CpG -180 methylation with age ( Figure 3 ).

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