UU/UA dinucleotide frequency reduction in coding regions results in increased mRNA stability and protein expression.

Mol Ther · 2012 · PMC3345983 · PMID 22434136

Europe PMC DOI

hedged sentence

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

marginal significanceP = 0.06so close (0.05 < p ≤ 0.1)

A marginal significance ( P = 0.06) was observed for the UW -reduced HBsAg construct, but this small increase (19% increase) played only a little role in the substantial increase in protein expression (400%, Figure 1c ).

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