We have previously shown that 4 wks administration of the diet rich in trans FA (60 cal% fat; 50% of fat in the form of trans MUFA) resulted in a highly significant elevation of TNFα and IL-1β expression in the liver [ 54 ].
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Kupffer cells ameliorate hepatic insulin resistance induced by high-fat diet rich in monounsaturated fatty acids: the evidence for the involvement of alternatively activated macrophages.
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