In both male and female liver, genes up regulated from 3 wk to 8 wk showed highly significant enrichment for genes positively regulated by HNF4α ( p = E-77 to E-110), and genes down regulated from 3 wk to 8 wk showed highly significant enrichment for the set of genes negatively regulated by HNF4α ( p = E-66 to E-67) (Table 2 ).
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Sex-specific mouse liver gene expression: genome-wide analysis of developmental changes from pre-pubertal period to young adulthood.
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