Additionally, β-catenin has been associated with epidermal growth factor receptor (EGFR) family members [12] – [16] and the stability of β-catenin and its TCF/LEF-activating function has been suggested to be regulated via tyrosine phosphorylation by the EGFR family [15] , [17] – [19] , which may be significant for breast carcinogenesis, since human epidermal growth factor receptor 2 (HER2) is overexpressed in about 30% of human breast tumors [20] , [21] .
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