Dehydroepiandrosterone biosynthesis, role, and mechanism of action in the developing neural tube.

The presence of DHEA in the culture medium increased the percentage of Nkx6.1+ cells (Figures 4 A,B), but not that of Pax6+ cells (Figure 4 C), at the early time points, with highly significant differences between the DHEA-treated and control cultures at 7–10 h and 18–21 h).

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