Our finding on the inhibitory effect of miR-379 on Smad signaling is consistent with our gene expression profiling analysis showing a highly significant correlation between the genes downregulated by miR-379 and two previously published gene sets: genes upregulated in basal subtype of clinical breast cancer samples and genes downregulated in luminal-like breast cancer cell lines as compared to the mesenchymal-like ones.
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Identification of microRNAs inhibiting TGF-β-induced IL-11 production in bone metastatic breast cancer cells.
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