Ubiquitous [Na+]i/[K+]i-sensitive transcriptome in mammalian cells: evidence for Ca(2+)i-independent excitation-transcription coupling.

Importantly, we observed highly significant (p<0.0003) and positive (R 2 >0.62) correlations between levels of differentially expressed transcripts identified in the presence of ouabain and K + -free medium ( Fig. 4 ).

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