Differential pattern and prognostic significance of CD4+, FOXP3+ and IL-17+ tumor infiltrating lymphocytes in ductal and lobular breast cancers.

BMC Cancer · 2012 · PMC3362763 · PMID 22471961

Europe PMC DOI

hedged sentences

0.0200

closest p · 0.4× alpha

0.0480

boldest claim

The sentences

an overall trendp = 0.02actually significant

Notably, an overall trend ( p = 0.02) suggesting an association between total number of FOXP3 + TIL and higher tumor stage could be observed (Stage IA: 7.1 ± 13.6, Stage IIA: 7.9 ± 13.3, Stage IIB: 7.9 ± 13.7 and Stage: IIIA: 9.5 ± 15.8).

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a slight trendp = 0.048actually significant

Only very few IL-17 + lymphocytes were detected in either cancer subtype (ductal: 1.4 ± 3.0; lobular: 2.4 ± 5.4, p = 0.046), with a slight trend towards relatively higher counts in the stromal compartment of lobular as compared to ductal carcinomas (1.1 ± 2.3 vs. 1.8 ± 3.4; p = 0.048).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.