We consistently observed an increasing trend of the proportion of CD39 + Foxp3 + Tregs in total Foxp3 + Tregs in the CD39low (17%), CD39int (45%) and CD39high (65%) groups (Figure 1B ), in accordance with the hypothesis that the CD39 surface marker could be used for routine isolation of functional human Tregs [ 27 ].
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Expression of CD39 on FoxP3+ T regulatory cells correlates with progression of HBV infection.
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