Is there a role for the quantification of RRM1 and ERCC1 expression in pancreatic ductal adenocarcinoma?

BMC Cancer · 2012 · PMC3364898 · PMID 22436573

Europe PMC DOI

hedged sentences

0.0700

closest p · 1.4× alpha

0.0700

boldest claim

The sentences

a trend toward significanceP = 0.07so close (0.05 < p ≤ 0.1)

showed a trendP = 0.07so close (0.05 < p ≤ 0.1)

Indeed, when analyzing only those patients who received a complete regimen of chemotherapy, high RRM1 gene expression (PCR) showed a trend toward significance ( P = 0.07) but the number of patients investigated was too small (N = 7) and results could be due to random sampling variability.

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borderline significantP = 0.07so close (0.05 < p ≤ 0.1)

In regards to the correlation between IHC and PCR analysis, we found a borderline significant association between RRM1 expression by IHC and PCR (r = 0.26; P = 0.07) and the same result was applicable for ERCC1 expression (r = 0.21; P = 0.07).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.