Barely Significant
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Inhibition of hepatitis C virus replication and viral helicase by ethyl acetate extract of the marine feather star Alloeocomatella polycladia.

Mar Drugs · 2012 · PMC3366673 · PMID 22690141

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highly significantno p-value reported
Thus, marine natural products are considered to include highly significant lead compounds for drug development [ 30 , 31 ].

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.