Lactate, a product of glycolytic metabolism, inhibits histone deacetylase activity and promotes changes in gene expression.

Nucleic Acids Res · 2012 · PMC3367171 · PMID 22323521

Europe PMC DOI

hedged sentence

0.0001

closest p · 0.0× alpha

0.0001

boldest claim

The sentences

highly significantP < 0.0001actually significant

Chi-squared tests demonstrated that all differences between the observed overlap, and the overlap expected by chance were highly significant ( P < 0.0001).

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