A gene variant near ATM is significantly associated with metformin treatment response in type 2 diabetes: a replication and meta-analysis of five cohorts.

Diabetologia · 2012 · PMC3369131 · PMID 22453232

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highly significantno p-value reported

To avoid an overestimation of the effect of the SNP, the initial GoDARTS discovery cohort, which showed a very strong and highly significant association with treatment success (OR 1.64; 95% CI 1.37, 1.99), was not included.

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