Barely Significant
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A seven-marker signature and clinical outcome in malignant melanoma: a large-scale tissue-microarray study with two independent patient cohorts.

PLoS One · 2012 · PMC3369875 · PMID 22685558

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hedged sentence
0.0001
closest p · 0.0× alpha
0.0001
boldest claim

The sentences

highly significantp<0.0001actually significant
The difference in survival expectance between patients with high-risk score and low-risk score was highly significant (p<0.0001).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.