Barely Significant
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Effect of beta-1-blocker, nebivolol, on central aortic pressure and arterial stiffness in patients with essential hypertension.

Indian J Pharmacol · 2012 · PMC3371470 · PMID 22701257

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may be significantno p-value reported
They allow relatively simple estimation of central pressures (particularly indices independent from the absolute values of BP), with high reproducibility.[ 3 ] Although different drugs reduce peripheral BP to some extent there may be significant differences in their effect on central BP reduction.

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