[(11)C]Doxepin binding to histamine H1 receptors in living human brain: reproducibility during attentive waking and circadian rhythm.

There was an apparent trend for decreased BP in the afternoon, but the BP values in the brain regions including anterior cingulate gyrus were not significantly higher in the morning test trial (Figure 3B ), demonstrating that [ 11 C]doxepin binding in the brain is essentially the same between in the morning and afternoon.

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