4 5 Similar reasoning may be applied to explain the highly significant difference in radiographic progression observed between placebo + MTX and golimumab + MTX despite only an intermediary level of baseline inflammation compared with previously conducted trials of golimumab. 4 5 16 Finally, more patients met the EE criteria in the golimumab 50 mg + MTX group (Group 2) than in the golimumab 100 mg + MTX group (Group 3), indicating the potential for a dose response.
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Golimumab in combination with methotrexate in Japanese patients with active rheumatoid arthritis: results of the GO-FORTH study.
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