did not achieve significancep = 0.07
Although there was a trend towards a reduced incidence of lung metastases in mice bearing Y477F ezrin tumors (both A43 and C13 clones), this difference did not achieve significance ( p = 0.07, Figure 5A ).
Although there was a trend towards a reduced incidence of lung metastases in mice bearing Y477F ezrin tumors (both A43 and C13 clones), this difference did not achieve significance ( p = 0.07, Figure 5A ).
While Y477F ezrin was found to have a marked attenuating effect on local invasion during early phases of tumor growth, a reduction in the proportion of mice with distant metastasis was also observed, though this effect failed to reach significance.