Lysyl oxidase-like 2 (LOXL2), a new regulator of cell polarity required for metastatic dissemination of basal-like breast carcinomas.

Furthermore, LOXL2 silencing resulted in a highly significant decrease of the invasion capacity of MDA-MB-231 cells ( Fig 2I ) while their proliferation in bi-dimensional cultures was not significantly affected ( Fig 2J ), in agreement with a recent report (Barker et al, 2011 ).

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