Oncogene addiction as a foundational rationale for targeted anti-cancer therapy: promises and perils.

EMBO Mol Med · 2011 · PMC3377106 · PMID 21953712

Europe PMC DOI

hedged sentence

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closest p

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boldest claim

The sentences

highly significantno p-value reported

The rapid implementation of Phase 1 information into large, randomized Phase 3 trials is a clear sign of the power of early studies when these are supported by a strong biological rationale and by highly significant responses.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.