Systemic RNAi-mediated Gene Silencing in Nonhuman Primate and Rodent Myeloid Cells.

Mol Ther Nucleic Acids · 2012 · PMC3381593 · PMID 23344621

Europe PMC DOI

hedged sentence

0.0000

closest p · 0.0× alpha

0.0000

boldest claim

The sentences

highly significantP < 10 −5actually significant

In splenic macrophages from arthritic mice treated with TNFα targeting but not with control siRNA, we found a decrease of intracellular TNFα staining indicating effective silencing ( Figure 6b ).Overall, the effect of treatment on mean fluorescent intensity value is highly significant according to an ANOVA ( F = 17.061, P < 10 −5 ).

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.