LINE-1 hypomethylation in familial and sporadic cancer.

J Mol Med (Berl) · 2012 · PMC3383956 · PMID 22228215

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a decreasing trendno p-value reported

Interestingly, normal colorectal mucosa samples from different patient groups displayed differences in LINE-1 methylation that mirrored differences between the respective tumor tissues, with a decreasing trend for LINE-1 methylation from patients with sporadic colorectal cancer to LS to FCCX.

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