Furthermore, another study of bevacizumab-treated rats bearing human glioblastoma multiforme tumors demonstrated, “a strong and highly significant increase in the number of tumor cells invading the normal brain” [ 26 ], suggesting a negative effect on tumor biology in that setting.
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Regulator of G-Protein Signaling 5 Reduces HeyA8 Ovarian Cancer Cell Proliferation and Extends Survival in a Murine Tumor Model.
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