Bladder cancer diagnosis and identification of clinically significant disease by combined urinary detection of Mcm5 and nuclear matrix protein 22.

PLoS One · 2012 · PMC3392249 · PMID 22792272

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a decreasing trendno p-value reported

There was evidence of a decreasing trend in the false-negative rate with increasing tumour grade and stage for both urinary biomarkers.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.