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Investigating international time trends in the incidence and prevalence of atopic eczema 1990-2010: a systematic review of epidemiological studies.

PLoS One · 2012 · PMC3394782 · PMID 22808063

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an increasing trendno p-value reported
The lifetime prevalence of physician-diagnosed atopic eczema showed an increasing trend in 6–7 year olds in Italy [from 14.3% (1994–95) to 17.0% (2002)] [66] and in the same age group in Portugal [from 18.6% (1993–94) to 21.0% (2002)] [67] .

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.