The Chemical Interplay between Nitric Oxide and Mitochondrial Cytochrome c Oxidase: Reactions, Effectors and Pathophysiology.

Int J Cell Biol · 2012 · PMC3395247 · PMID 22811713

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almost insignificantno p-value reported

Both in state 3 and state 4, if the NO concentration is low (e.g., subnanomolar), the fraction of CcOX inhibited is limited, and the depression of respiration is almost insignificant [ 77 , 78 ], a finding consistent with an excess capacity of CcOX [ 79 , 80 ].

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