Variability of plasma and urine betaine in diabetes mellitus and its relationship to methionine load test responses: an observational study.

The three strongest candidate predictors (all log-transformed) were included in an explicit multiple linear regression model (Figure 2 ) which confirmed that the fasting plasma homocysteine was the strongest (positive) predictor, and the post-methionine load plasma betaine concentration was also a highly significant ( p < 0.001) negative predictor.

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