The WIZARD (Weekly Intervention with Zithromax for Atherosclerosis and its Related Disorders) study failed to find a long-term benefit, even though a favorable trend was noted during and shortly after 3 months of azithromycin treatment. 12 More recent trials, ACES (Azithromycin and Coronary Events Study) 13 and PROVE IT-TIMI 22 (Pravastatin Or Atorvastatin Evaluation and Infection Therapy), 14 also reported a negative outcome.
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Oral azithromycin in extended dosage schedule for chronic, subclinical Chlamydia pneumoniae infection causing coronary artery disease: a probable cure in sight? Results of a controlled preliminary trial.
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