A CD4 T cell gene signature for early rheumatoid arthritis implicates interleukin 6-mediated STAT3 signalling, particularly in anti-citrullinated peptide antibody-negative disease.

Ann Rheum Dis · 2012 · PMC3396452 · PMID 22532634

Europe PMC DOI

hedged sentence

0.0000

closest p · 0.0× alpha

0.0000

boldest claim

The sentences

highly significantp<1.0×10−5actually significant

A highly significant over-representation of genes involved in the cell cycle was identified in association with ACPA-positive RA (24/43; p<1.0×10−5); figure 2 ; online supplementary gene-list 5).

also in 132,142 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.