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A dynamic model of circadian rhythms in rodent tail skin temperature for comparison of drug effects.

J Circadian Rhythms · 2012 · PMC3398330 · PMID 22221596

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an overall trendno p-value reported
As an improvement to these models, an overall trend in temperature baseline has been included, and, most importantly, separate day- and nighttime variances are used to account for varying levels of activity and excitement at different times of the day.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.