Quiescent keratocytes fail to repair MMC induced DNA damage leading to the long-term inhibition of myofibroblast differentiation and wound healing.

Mol Vis · 2012 · PMC3398499 · PMID 22815636

Europe PMC

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may be significantno p-value reported

While it is not known whether a similar mechanism underlies the anti-fibrotic effect of MMC in patients receiving refractive surgery, these findings suggest that there may be significant long-term consequences for MMC therapy.

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