Glycogen synthase kinase-3 inhibition sensitizes pancreatic cancer cells to TRAIL-induced apoptosis.

PLoS One · 2012 · PMC3400624 · PMID 22829912

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highly significantno p-value reported

Interestingly, although there was variation in TRAIL sensitivity among the tested cell lines, with PANC-1 being the most TRAIL resistant, the combination with GSK-3 suppression provided a consistent and highly significant sensitization to TRAIL in all the cell lines tested.

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