Results of these trials have shown significant prolongation of progression free survival (PFS) with the addition of bevacizumab to standard doublet chemotherapy, with ICON 7 showing also a favorable trend in overall survival (OS), based on which the European Medicines Agency (EMA) has recently approved its use in EOC on 4 th October 2011 [ 15 ].
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A case series of low dose bevacizumab and chemotherapy in heavily pretreated patients with epithelial ovarian cancer.
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