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ChIPnorm: a statistical method for normalizing and identifying differential regions in histone modification ChIP-seq libraries.

PLoS One · 2012 · PMC3411705 · PMID 22870189

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an increasing trendno p-value reported
We see from the figure that there is an increasing trend of ChIP-seq fragments with gene density.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.