Genome-wide analysis of germline signaling genes regulating longevity and innate immunity in the nematode Pristionchus pacificus.

Interestingly, we found extensive and highly significant overlap between the genes regulated upon germline ablation and the pathogen response genes known in P. pacificus (our unpublished data), particularly those regulated by exposure to gram-negative pathogens S. marcescens and X. nematophila ( Table 1 ).

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