A novel role for transcription factor Lmo4 in thymus development through genetic interaction with Cited2.

Dev Dyn · 2010 · PMC3417300 · PMID 20549734

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highly significantP = 0.00006actually significant

Cited2 −/− embryos showed a modest yet highly significant decrease in levels of Lmo4 mRNA when compared with wild-type littermates (1.35-fold decrease; P = 0.00006, n = 12 Cited2 +/+ vs. n = 12 Cited2 −/− embryos), but Lmo4 −/− embryos did not show any difference in Cited2 levels (n = 12 Lmo4 +/+ vs. n = 12 Lmo4 −/− embryos; Fig. 5 a,b), indicating that Lmo4 is downstream of Cited2 .

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