5 , 6 Although the HOMA-IR is a static measure, it has been validated against the clamp 6 and used extensively in adolescents, with a value of 3.16 proposed as the low value, above which there may be significant IR in adolescents. 4 While the HOMA-IR provides a reasonable estimate of insulin resistance, it is rarely performed without an initial degree of clinical suspicion.
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Prediction of insulin resistance with anthropometric measures: lessons from a large adolescent population.
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The sentences
Although both models were highly significant in their prediction of Ln(HOMA-IR), the model for males (r 2 = 0.427) predicted a higher percentage of variance than did the model for females (r 2 = 0.275).