New developments in the treatment of actinic keratosis: focus on ingenol mebutate gel.

57 Results for the primary endpoint of complete clearance were also highly significant, favoring ingenol mebutate in each of the four individual studies ( P < 0.001). 57 The efficacy of ingenol mebutate varied according to anatomic location, with higher rates of complete clearance associated with facial AK (ingenol mebutate versus vehicle, 47.3% versus 4.1%; P < 0.001) than with scal

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