Barely Significant
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Secretome survey of human plexiform neurofibroma derived Schwann Cells reveals a secreted form of the RARRES1 protein.

Int J Mol Sci · 2012 · PMC3430302 · PMID 22942771

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highly significantno p-value reported
The dramatic decrease of PAI-1 in the extracellular milieu of NF1 Schwann cells relative to normal Schwann cells is also highly significant in the context of neurofibroma growth and progression.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.